Interleukin-12 receptor

interleukin 12 receptor, beta 1
Identifiers
SymbolIL12RB1
Alt. symbolsIL12RB, CD212
NCBI gene3594
HGNC5971
OMIM601604
RefSeqNM_005535
UniProtP42701
Other data
LocusChr. 19 p13.1
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StructuresSwiss-model
DomainsInterPro
beta 2 subunit, interleukin 12 receptor, beta 2
Identifiers
SymbolIL12RB2
NCBI gene3595
HGNC5972
OMIM601642
RefSeqNM_001559
UniProtQ99665
Other data
LocusChr. 1 p31.3-31.2
Search for
StructuresSwiss-model
DomainsInterPro

Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12 and consisting of beta 1[1] and beta 2 subunits.[2]

References

  1. ^ Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130". J. Immunol. 153 (1): 128–36. doi:10.4049/jimmunol.153.1.128. PMID 7911493. S2CID 9211163.
  2. ^ Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–14007. Bibcode:1996PNAS...9314002P. doi:10.1073/pnas.93.24.14002. PMC 19484. PMID 8943050.


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